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Vaxcyte, Inc. (PCVX) vs Twist Bioscience Corporation (TWST)

Vaxcyte, Inc. and Twist Bioscience Corporation are both Biotechnology companies. Vaxcyte, Inc. and Twist Bioscience Corporation are of similar size ($10.1B and $9.8B). Vaxcyte, Inc. has the higher net margin (0.00% vs −31.7%) and the lower return on invested capital (−57.3% vs −30.8%). Across the 14 metrics below, Vaxcyte, Inc. leads on 7 and Twist Bioscience Corporation on 7.

Valuation

Metric PCVX TWST Biotechnology median
P/E n/m n/m 12.43
P/S n/m 22.08 10.53
P/B 3.25 21.39 2.24
Price to free cash flow n/m n/m 22.59
EV/EBITDA n/m n/m 0.69
EV/Sales n/m 21.73 9.92
Earnings yield (12.30%) (1.45%) (34.94%)
Free cash flow yield (9.98%) (1.00%) (23.17%)

Profitability

Metric PCVX TWST Biotechnology median
Gross margin 0.00% 51.97% 68.94%
Operating margin 0.00% (33.58%) 0.00%
Net margin 0.00% (31.66%) 0.00%
Free cash flow margin 0.00% (22.15%) 0.00%
Return on equity (36.51%) (29.59%) (54.09%)
Return on assets (33.03%) (20.78%) (46.84%)
Return on invested capital (57.30%) (30.83%) 0.00%

Growth

Metric PCVX TWST Biotechnology median
Revenue growth (TTM) — 19.19% 6.72%
EPS growth (last fiscal year) (48.16%) 63.89% 29.36%
Revenue growth, 5-year CAGR — 33.11% 9.96%
Net income growth, 5-year CAGR 0.00% 0.00% 0.00%

Health

Metric PCVX TWST Biotechnology median
Debt to equity 0.00 0.03 0.00
Current ratio 5.72 2.67 5.00
Net debt to EBITDA 1.71 1.95 1.01

Dividend

Metric PCVX TWST Biotechnology median
Dividend yield — — 0.40%
Payout ratio — — —

Size

Metric PCVX TWST Biotechnology median
Market cap 9.76b 10.06b 177.44m

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