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Neurogene Inc. (NGNE) vs Puma Biotechnology, Inc. (PBYI)

Neurogene Inc. and Puma Biotechnology, Inc. are both Biotechnology companies. Neurogene Inc. and Puma Biotechnology, Inc. are of similar size ($513.3M and $504.3M). Neurogene Inc. has negative trailing earnings, so its P/E is not meaningful; Puma Biotechnology, Inc. trades at 15.3×. Puma Biotechnology, Inc. has the higher net margin (11.6% vs 0.00%) and the higher return on invested capital (42.6% vs 0.00%). Across the 13 metrics below, Puma Biotechnology, Inc. leads on 10 and Neurogene Inc. on 3.

Valuation

Metric NGNE PBYI Biotechnology median
P/E n/m 15.31 10.60
P/S n/m 1.82 9.40
P/B 2.63 3.04 2.13
Price to free cash flow n/m 14.74 25.18
EV/EBITDA n/m 8.54 0.66
EV/Sales n/m 1.51 9.02
Earnings yield (19.89%) 6.53% (32.88%)
Free cash flow yield (15.38%) 6.78% (23.13%)

Profitability

Metric NGNE PBYI Biotechnology median
Gross margin 0.00% 74.83% 68.51%
Operating margin 0.00% 13.16% 0.00%
Net margin 0.00% 11.55% 0.00%
Free cash flow margin 0.00% 17.79% 0.00%
Return on equity (45.32%) 21.97% (51.96%)
Return on assets (41.02%) 13.78% (46.06%)
Return on invested capital 0.00% 42.61% 0.00%

Growth

Metric NGNE PBYI Biotechnology median
Revenue growth (TTM) — (2.86%) 6.76%
EPS growth (last fiscal year) 0.93% (1.61%) 29.88%
Revenue growth, 5-year CAGR — 0.29% 9.75%
Net income growth, 5-year CAGR 0.00% 0.00% 0.00%

Health

Metric NGNE PBYI Biotechnology median
Debt to equity 0.00 0.00 0.00
Current ratio 10.64 2.91 4.97
Net debt to EBITDA 2.57 (1.60) 1.01

Dividend

Metric NGNE PBYI Biotechnology median
Dividend yield — — 0.41%
Payout ratio — — —

Size

Metric NGNE PBYI Biotechnology median
Market cap 513.29m 504.33m 161.82m

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