Mirum Pharmaceuticals, Inc. (MIRM) vs Rhythm Pharmaceuticals, Inc. (RYTM)

Mirum Pharmaceuticals, Inc. and Rhythm Pharmaceuticals, Inc. are both Biotechnology companies. Rhythm Pharmaceuticals, Inc. is the larger, with a market value of $6.8B against $5.8B — 1.2× the size. Rhythm Pharmaceuticals, Inc. grew revenue faster over the last twelve months: 53.5% against 44.0%. Rhythm Pharmaceuticals, Inc. has the higher net margin (−87.6% vs −139.2%) and the higher return on invested capital (0.00% vs −173.0%). Across the 16 metrics below, Rhythm Pharmaceuticals, Inc. leads on 11 and Mirum Pharmaceuticals, Inc. on 5.

Valuation

Metric MIRM RYTM Biotechnology median
P/E n/m n/m 7.88
P/S 9.20 28.21 11.47
P/B n/m 65.71 2.52
Price to free cash flow n/m n/m 21.16
EV/EBITDA n/m n/m 0.74
EV/Sales 9.70 26.83 10.73
Earnings yield (16.21%) (3.15%) (28.84%)
Free cash flow yield (4.82%) (2.23%) (23.03%)

Profitability

Metric MIRM RYTM Biotechnology median
Gross margin 81.72% 89.00% 65.16%
Operating margin (134.93%) (83.62%) 0.00%
Net margin (139.18%) (87.62%) 0.00%
Free cash flow margin (44.29%) (43.91%) 0.00%
Return on equity (702.97%) (461.65%) (57.72%)
Return on assets (97.15%) (51.91%) (49.22%)
Return on invested capital (172.96%) 0.00% 0.00%

Growth

Metric MIRM RYTM Biotechnology median
Revenue growth (TTM) 44.02% 53.51% 5.64%
EPS growth (last fiscal year) 74.59% 28.34% —
Revenue growth, 5-year CAGR — — 8.40%
Net income growth, 5-year CAGR 0.00% 0.00% 0.00%

Health

Metric MIRM RYTM Biotechnology median
Debt to equity (71.97) 0.00 0.00
Current ratio 2.86 3.45 4.73
Net debt to EBITDA (19.11) 2.04 0.96

Dividend

Metric MIRM RYTM Biotechnology median
Dividend yield — — 2.10%
Payout ratio 0.00 0.00 0.00

Size

Metric MIRM RYTM Biotechnology median
Market cap 5.84b 6.77b 162.10m

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