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ICON PLC (ICLR) vs Twist Bioscience Corporation (TWST)

ICON PLC and Twist Bioscience Corporation are both Diagnostics & Research companies. ICON PLC is the larger, with a market value of $13.5B against $9.5B — 1.4× the size. Twist Bioscience Corporation has negative trailing earnings, so its P/E is not meaningful; ICON PLC trades at 254×. Twist Bioscience Corporation grew revenue faster over the last twelve months: 19.2% against 3.26%. ICON PLC has the higher net margin (0.51% vs −31.7%) and the higher return on invested capital (1.57% vs −30.8%). Across the 19 metrics below, ICON PLC leads on 11 and Twist Bioscience Corporation on 8.

Valuation

Metric ICLR TWST Diagnostics & Research median
P/E 254.23 n/m 35.56
P/S 1.58 19.18 4.37
P/B 1.39 18.58 3.06
Price to free cash flow 14.80 n/m 35.76
EV/EBITDA 23.30 n/m 24.35
EV/Sales 1.87 18.84 5.51
Earnings yield 0.39% (1.67%) (1.89%)
Free cash flow yield 6.76% (1.15%) (0.15%)

Profitability

Metric ICLR TWST Diagnostics & Research median
Gross margin 23.91% 51.97% 50.89%
Operating margin 3.57% (33.58%) (8.57%)
Net margin 0.51% (31.66%) (6.37%)
Free cash flow margin 10.66% (22.15%) 0.00%
Return on equity 0.45% (29.59%) (2.92%)
Return on assets 0.26% (20.78%) (6.71%)
Return on invested capital 1.57% (30.83%) 0.00%

Growth

Metric ICLR TWST Diagnostics & Research median
Revenue growth (TTM) 3.26% 19.19% 7.69%
EPS growth (last fiscal year) (69.57%) 63.89% 25.92%
Revenue growth, 5-year CAGR 24.15% 33.11% 7.40%
Net income growth, 5-year CAGR (7.15%) 0.00% 0.00%

Health

Metric ICLR TWST Diagnostics & Research median
Debt to equity 0.36 0.03 0.11
Current ratio 0.95 2.67 2.02
Net debt to EBITDA 3.34 1.95 0.70

Dividend

Metric ICLR TWST Diagnostics & Research median
Dividend yield — — 0.66%
Payout ratio — — 0.20

Size

Metric ICLR TWST Diagnostics & Research median
Market cap 13.51b 9.51b 2.16b

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