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Gyre Therapeutics, Inc. (GYRE) vs Prothena Corporation plc (PRTA)

Gyre Therapeutics, Inc. and Prothena Corporation plc are both Biotechnology companies. Gyre Therapeutics, Inc. and Prothena Corporation plc are of similar size ($425.2M and $405.1M). Prothena Corporation plc grew revenue faster over the last twelve months: 347.4% against 13.5%. Gyre Therapeutics, Inc. has the higher net margin (−21.5% vs −45.4%) and the lower return on invested capital (−8.51% vs 0.00%). Across the 17 metrics below, Prothena Corporation plc leads on 10 and Gyre Therapeutics, Inc. on 7.

Valuation

Metric GYRE PRTA Biotechnology median
P/E n/m n/m 10.60
P/S 4.12 7.76 9.40
P/B 3.47 1.52 2.13
Price to free cash flow n/m n/m 25.18
EV/EBITDA n/m n/m 0.66
EV/Sales 3.55 2.62 9.02
Earnings yield (5.93%) (5.90%) (32.88%)
Free cash flow yield (5.07%) (7.86%) (23.13%)

Profitability

Metric GYRE PRTA Biotechnology median
Gross margin 91.71% 100.00% 68.51%
Operating margin 0.00% (64.64%) 0.00%
Net margin (21.46%) (45.43%) 0.00%
Free cash flow margin (19.94%) (61.03%) 0.00%
Return on equity (18.54%) (8.50%) (51.96%)
Return on assets (14.49%) (7.53%) (46.06%)
Return on invested capital (8.51%) 0.00% 0.00%

Growth

Metric GYRE PRTA Biotechnology median
Revenue growth (TTM) 13.51% 347.44% 6.76%
EPS growth (last fiscal year) (60.00%) (99.56%) 29.88%
Revenue growth, 5-year CAGR 40.96% 62.56% 9.75%
Net income growth, 5-year CAGR 0.00% 0.00% 0.00%

Health

Metric GYRE PRTA Biotechnology median
Debt to equity 0.00 0.00 0.00
Current ratio 4.32 23.95 4.97
Net debt to EBITDA (3.74) 1.46 1.01

Dividend

Metric GYRE PRTA Biotechnology median
Dividend yield — — 0.41%
Payout ratio — — —

Size

Metric GYRE PRTA Biotechnology median
Market cap 425.20m 405.05m 161.82m

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