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Cue Biopharma, Inc. (CUE) vs Spruce Biosciences, Inc. (SPRB)

Cue Biopharma, Inc. and Spruce Biosciences, Inc. are both Biotechnology companies. Cue Biopharma, Inc. and Spruce Biosciences, Inc. are of similar size ($136.1M and $133.8M). Cue Biopharma, Inc. grew revenue faster over the last twelve months: 354.4% against −51.3%. Spruce Biosciences, Inc. has the higher net margin (0.00% vs −435.8%) and the higher return on invested capital (0.00% vs 0.00%). Across the 15 metrics below, Spruce Biosciences, Inc. leads on 9 and Cue Biopharma, Inc. on 6.

Valuation

Metric CUE SPRB Biotechnology median
P/E n/m n/m 10.60
P/S 3.15 23.04 9.40
P/B 51.41 1.35 2.13
Price to free cash flow n/m n/m 25.18
EV/EBITDA n/m n/m 0.66
EV/Sales 2.74 4.88 9.02
Earnings yield (143.53%) (88.60%) (32.88%)
Free cash flow yield (42.21%) (37.80%) (23.13%)

Profitability

Metric CUE SPRB Biotechnology median
Gross margin 100.00% 100.00% 68.51%
Operating margin (262.03%) 0.00% 0.00%
Net margin (435.83%) 0.00% 0.00%
Free cash flow margin (133.13%) 0.00% 0.00%
Return on equity (1,603.48%) (105.98%) (51.96%)
Return on assets (459.60%) (82.38%) (46.06%)
Return on invested capital 0.00% 0.00% 0.00%

Growth

Metric CUE SPRB Biotechnology median
Revenue growth (TTM) 354.37% (51.32%) 6.76%
EPS growth (last fiscal year) 61.11% 47.59% 29.88%
Revenue growth, 5-year CAGR 54.16% — 9.75%
Net income growth, 5-year CAGR 0.00% 0.00% 0.00%

Health

Metric CUE SPRB Biotechnology median
Debt to equity 0.00 0.08 0.00
Current ratio 1.25 9.23 4.97
Net debt to EBITDA 1.10 1.34 1.01

Dividend

Metric CUE SPRB Biotechnology median
Dividend yield — — 0.41%
Payout ratio — — —

Size

Metric CUE SPRB Biotechnology median
Market cap 136.06m 133.79m 161.82m

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