Corcept Therapeutics Incorporated (CORT) vs Spyre Therapeutics, Inc. (SYRE)

Corcept Therapeutics Incorporated and Spyre Therapeutics, Inc. are both Biotechnology companies. Spyre Therapeutics, Inc. is the larger, with a market value of $9.2B against $7.8B — 1.2× the size. Spyre Therapeutics, Inc. has negative trailing earnings, so its P/E is not meaningful; Corcept Therapeutics Incorporated trades at 47.5×. Corcept Therapeutics Incorporated grew revenue faster over the last twelve months: 30.0% against −81.8%. Corcept Therapeutics Incorporated has the higher net margin (16.5% vs 0.00%) and the higher return on invested capital (15.0% vs 0.00%). Across the 18 metrics below, Corcept Therapeutics Incorporated leads on 14 and Spyre Therapeutics, Inc. on 4.

Valuation

Metric CORT SYRE Biotechnology median
P/E 47.47 n/m 10.26
P/S 7.98 8,159.98 9.18
P/B 9.22 9.50 2.05
Price to free cash flow 39.51 n/m 24.81
EV/EBITDA 67.42 n/m 0.65
EV/Sales 7.61 7,142.99 8.98
Earnings yield 2.11% (3.16%) (34.89%)
Free cash flow yield 2.53% (2.89%) (24.52%)

Profitability

Metric CORT SYRE Biotechnology median
Gross margin 98.54% 100.00% 65.16%
Operating margin 11.51% 0.00% 0.00%
Net margin 16.54% 0.00% 0.00%
Free cash flow margin 20.20% 0.00% 0.00%
Return on equity 21.74% (41.15%) (50.12%)
Return on assets 17.16% (30.89%) (45.60%)
Return on invested capital 14.97% 0.00% 0.00%

Growth

Metric CORT SYRE Biotechnology median
Revenue growth (TTM) 30.02% (81.84%) 6.26%
EPS growth (last fiscal year) (33.33%) 55.24% 29.88%
Revenue growth, 5-year CAGR 16.56% (28.15%) 9.75%
Net income growth, 5-year CAGR (1.52%) 0.00% 0.00%

Health

Metric CORT SYRE Biotechnology median
Debt to equity 0.00 0.00 0.00
Current ratio 3.00 27.40 4.89
Net debt to EBITDA (8.83) 3.61 1.01

Dividend

Metric CORT SYRE Biotechnology median
Dividend yield — — 0.41%
Payout ratio — — —

Size

Metric CORT SYRE Biotechnology median
Market cap 7.84b 9.17b 172.11m

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