CareDx, Inc. (CDNA) vs OPKO Health, Inc. (OPK)

CareDx, Inc. and OPKO Health, Inc. are both Diagnostics & Research companies. CareDx, Inc. is the larger, with a market value of $3.2B against $1.2B — 2.6× the size. OPKO Health, Inc. has negative trailing earnings, so its P/E is not meaningful; CareDx, Inc. trades at 29.6×. CareDx, Inc. grew revenue faster over the last twelve months: 34.4% against −11.5%. CareDx, Inc. has the higher net margin (24.2% vs −12.4%) and the higher return on invested capital (130.1% vs −2.45%). Across the 19 metrics below, CareDx, Inc. leads on 15 and OPKO Health, Inc. on 4.

Valuation

Metric CDNA OPK Diagnostics & Research median
P/E 29.62 n/m 33.95
P/S 7.15 2.11 4.87
P/B 7.70 1.05 3.12
Price to free cash flow 39.42 n/m 34.02
EV/EBITDA 22.60 30.58 25.20
EV/Sales 6.42 2.19 5.66
Earnings yield 3.38% (5.49%) (1.75%)
Free cash flow yield 2.54% (11.60%) (0.13%)

Profitability

Metric CDNA OPK Diagnostics & Research median
Gross margin 70.58% 40.77% 50.89%
Operating margin 23.61% (8.21%) (8.57%)
Net margin 24.23% (12.40%) (6.37%)
Free cash flow margin 18.49% (22.75%) 0.00%
Return on equity 29.49% (5.88%) (2.92%)
Return on assets 22.72% (3.83%) (6.71%)
Return on invested capital 130.06% (2.45%) 0.00%

Growth

Metric CDNA OPK Diagnostics & Research median
Revenue growth (TTM) 34.41% (11.47%) 7.69%
EPS growth (last fiscal year) (143.01%) (275.00%) —
Revenue growth, 5-year CAGR 14.59% (15.82%) 7.40%
Net income growth, 5-year CAGR 0.00% 0.00% 0.00%

Health

Metric CDNA OPK Diagnostics & Research median
Debt to equity 0.00 0.29 0.11
Current ratio 4.58 3.35 2.02
Net debt to EBITDA 19.49 1.33 0.78

Dividend

Metric CDNA OPK Diagnostics & Research median
Dividend yield — — 0.70%
Payout ratio 0.00 0.00 0.00

Size

Metric CDNA OPK Diagnostics & Research median
Market cap 3.18b 1.22b 2.56b

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