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CalciMedica Inc. (CALC) vs SeaStar Medical Holding Corporation (ICU)

CalciMedica Inc. and SeaStar Medical Holding Corporation are both Biotechnology companies. SeaStar Medical Holding Corporation is the larger, with a market value of $10.2M against $8.9M — 1.1× the size. CalciMedica Inc. has the higher net margin (0.00% vs −795.5%) and the higher return on invested capital (0.00% vs 0.00%). Across the 13 metrics below, CalciMedica Inc. leads on 7 and SeaStar Medical Holding Corporation on 6.

Valuation

Metric CALC ICU Biotechnology median
P/E n/m n/m 10.26
P/S n/m 4.53 9.18
P/B 0.79 1.81 2.05
Price to free cash flow n/m n/m 24.81
EV/EBITDA 0.13 n/m 0.65
EV/Sales n/m 1.96 8.98
Earnings yield (527.34%) (205.79%) (34.89%)
Free cash flow yield (435.92%) (176.47%) (24.52%)

Profitability

Metric CALC ICU Biotechnology median
Gross margin 0.00% 92.64% 65.16%
Operating margin 0.00% (816.75%) 0.00%
Net margin 0.00% (795.50%) 0.00%
Free cash flow margin 0.00% (799.36%) 0.00%
Return on equity (365.70%) (356.87%) (50.12%)
Return on assets (110.10%) (160.02%) (45.60%)
Return on invested capital 0.00% 0.00% 0.00%

Growth

Metric CALC ICU Biotechnology median
Revenue growth (TTM) — 123.63% 6.26%
EPS growth (last fiscal year) (61.48%) 91.16% 29.88%
Revenue growth, 5-year CAGR — — 9.75%
Net income growth, 5-year CAGR 0.00% 0.00% 0.00%

Health

Metric CALC ICU Biotechnology median
Debt to equity 1.67 0.00 0.00
Current ratio 5.58 1.89 4.89
Net debt to EBITDA 0.14 0.99 1.01

Dividend

Metric CALC ICU Biotechnology median
Dividend yield — — 0.41%
Payout ratio — — —

Size

Metric CALC ICU Biotechnology median
Market cap 8.87m 10.20m 172.11m

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