Annovis Bio, Inc. (ANVS) vs Heron Therapeutics, Inc. (HRTX)

Annovis Bio, Inc. and Heron Therapeutics, Inc. are both Biotechnology companies. Annovis Bio, Inc. and Heron Therapeutics, Inc. are of similar size ($57.0M and $56.8M). Annovis Bio, Inc. has the higher net margin (0.00% vs −22.5%) and the higher return on invested capital (0.00% vs −6.35%). Across the 12 metrics below, Annovis Bio, Inc. leads on 7 and Heron Therapeutics, Inc. on 5.

Valuation

Metric ANVS HRTX Biotechnology median
P/E n/m n/m 7.88
P/S n/m 0.38 11.47
P/B n/m 9.75 2.52
Price to free cash flow n/m n/m 21.16
EV/EBITDA n/m n/m 0.74
EV/Sales n/m 1.04 10.73
Earnings yield (136.64%) (63.33%) (28.84%)
Free cash flow yield (88.18%) (21.17%) (23.03%)

Profitability

Metric ANVS HRTX Biotechnology median
Gross margin — 70.07% 65.16%
Operating margin 0.00% (7.19%) 0.00%
Net margin 0.00% (22.52%) 0.00%
Free cash flow margin 0.00% (8.00%) 0.00%
Return on equity (703.68%) 318.21% (57.72%)
Return on assets (227.74%) (14.06%) (49.22%)
Return on invested capital 0.00% (6.35%) 0.00%

Growth

Metric ANVS HRTX Biotechnology median
Revenue growth (TTM) — 0.99% 5.64%
EPS growth (last fiscal year) 39.39% (33.33%) —
Revenue growth, 5-year CAGR — 11.81% 8.40%
Net income growth, 5-year CAGR 0.00% 0.00% 0.00%

Health

Metric ANVS HRTX Biotechnology median
Debt to equity 0.00 20.65 0.00
Current ratio 3.47 2.49 4.73
Net debt to EBITDA 0.66 (643.88) 0.96

Dividend

Metric ANVS HRTX Biotechnology median
Dividend yield — — 2.10%
Payout ratio 0.00 0.00 0.00

Size

Metric ANVS HRTX Biotechnology median
Market cap 56.76m 56.96m 162.10m

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