Alto Neuroscience, Inc. (ANRO) vs Rigel Pharmaceuticals, Inc. (RIGL)

Alto Neuroscience, Inc. and Rigel Pharmaceuticals, Inc. are both Biotechnology companies. Alto Neuroscience, Inc. and Rigel Pharmaceuticals, Inc. are of similar size ($887.7M and $882.6M). Alto Neuroscience, Inc. has negative trailing earnings, so its P/E is not meaningful; Rigel Pharmaceuticals, Inc. trades at 2.6×. Rigel Pharmaceuticals, Inc. has the higher net margin (116.3% vs 0.00%) and the higher return on invested capital (16.5% vs 0.00%). Across the 13 metrics below, Rigel Pharmaceuticals, Inc. leads on 12 and Alto Neuroscience, Inc. on 1.

Valuation

Metric ANRO RIGL Biotechnology median
P/E n/m 2.60 8.50
P/S n/m 3.08 9.71
P/B 4.31 2.00 2.13
Price to free cash flow n/m 94.91 20.82
EV/EBITDA n/m 8.70 0.64
EV/Sales n/m 2.79 9.21
Earnings yield (10.97%) 38.44% (33.15%)
Free cash flow yield (7.29%) 1.05% (25.50%)

Profitability

Metric ANRO RIGL Biotechnology median
Gross margin — 91.39% 65.16%
Operating margin 0.00% 31.45% 0.00%
Net margin 0.00% 116.30% 0.00%
Free cash flow margin 0.00% 3.19% 0.00%
Return on equity (49.17%) 126.90% (56.36%)
Return on assets (40.90%) 88.46% (48.04%)
Return on invested capital 0.00% 16.48% 0.00%

Growth

Metric ANRO RIGL Biotechnology median
Revenue growth (TTM) — 3.31% 6.02%
EPS growth (last fiscal year) 12.40% 1,867.68% 30.26%
Revenue growth, 5-year CAGR — 22.06% 9.41%
Net income growth, 5-year CAGR — 0.00% 0.00%

Health

Metric ANRO RIGL Biotechnology median
Debt to equity 0.09 0.00 0.00
Current ratio 14.85 1.94 4.72
Net debt to EBITDA 2.40 (1.05) 0.96

Dividend

Metric ANRO RIGL Biotechnology median
Dividend yield — — 0.09%
Payout ratio — — —

Size

Metric ANRO RIGL Biotechnology median
Market cap 887.66m 882.62m 135.18m

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