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ADC Therapeutics SA (ADCT) vs Upstream Bio, Inc. (UPB)

ADC Therapeutics SA and Upstream Bio, Inc. are both Biotechnology companies. ADC Therapeutics SA and Upstream Bio, Inc. are of similar size ($190.2M and $184.6M). Upstream Bio, Inc. grew revenue faster over the last twelve months: 16.0% against 3.03%. ADC Therapeutics SA has the higher net margin (−121.8% vs −4,955.7%) and the higher return on invested capital (0.00% vs −1,100.9%). Across the 16 metrics below, ADC Therapeutics SA leads on 11 and Upstream Bio, Inc. on 5.

Valuation

Metric ADCT UPB Biotechnology median
P/E n/m n/m 8.50
P/S 2.75 47.69 9.71
P/B n/m 0.56 2.13
Price to free cash flow n/m n/m 20.82
EV/EBITDA n/m 0.65 0.64
EV/Sales 1.46 (35.05) 9.21
Earnings yield (46.81%) (105.07%) (33.15%)
Free cash flow yield (46.54%) (90.76%) (25.50%)

Profitability

Metric ADCT UPB Biotechnology median
Gross margin 88.86% 100.00% 65.16%
Operating margin (125.08%) (5,382.65%) 0.00%
Net margin (121.77%) (4,955.67%) 0.00%
Free cash flow margin (127.72%) (4,317.42%) 0.00%
Return on equity 45.35% (46.05%) (56.36%)
Return on assets (32.25%) (44.61%) (48.04%)
Return on invested capital 0.00% (1,100.93%) 0.00%

Growth

Metric ADCT UPB Biotechnology median
Revenue growth (TTM) 3.03% 15.98% 6.02%
EPS growth (last fiscal year) 30.86% 52.33% 30.26%
Revenue growth, 5-year CAGR 103.35% — 9.41%
Net income growth, 5-year CAGR 0.00% — 0.00%

Health

Metric ADCT UPB Biotechnology median
Debt to equity (0.51) 0.00 0.00
Current ratio 3.03 27.99 4.72
Net debt to EBITDA 1.22 2.11 0.96

Dividend

Metric ADCT UPB Biotechnology median
Dividend yield — — 0.09%
Payout ratio — — —

Size

Metric ADCT UPB Biotechnology median
Market cap 190.23m 184.58m 135.18m

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