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Actuate Therapeutics, Inc. (ACTU) vs SeaStar Medical Holding Corporation (ICU)

Actuate Therapeutics, Inc. and SeaStar Medical Holding Corporation are both Biotechnology companies. Actuate Therapeutics, Inc. is the larger, with a market value of $18.0M against $10.2M — 1.8× the size. Actuate Therapeutics, Inc. has the higher net margin (0.00% vs −795.5%) and the higher return on invested capital (0.00% vs 0.00%). Across the 11 metrics below, SeaStar Medical Holding Corporation leads on 6 and Actuate Therapeutics, Inc. on 5.

Valuation

Metric ACTU ICU Biotechnology median
P/E n/m n/m 10.26
P/S n/m 4.53 9.18
P/B 8.21 1.81 2.05
Price to free cash flow n/m n/m 24.81
EV/EBITDA n/m n/m 0.65
EV/Sales n/m 1.96 8.98
Earnings yield (255.88%) (205.79%) (34.89%)
Free cash flow yield (244.40%) (176.47%) (24.52%)

Profitability

Metric ACTU ICU Biotechnology median
Gross margin — 92.64% 65.16%
Operating margin 0.00% (816.75%) 0.00%
Net margin 0.00% (795.50%) 0.00%
Free cash flow margin 0.00% (799.36%) 0.00%
Return on equity 2,457.65% (356.87%) (50.12%)
Return on assets (336.18%) (160.02%) (45.60%)
Return on invested capital 0.00% 0.00% 0.00%

Growth

Metric ACTU ICU Biotechnology median
Revenue growth (TTM) — 123.63% 6.26%
EPS growth (last fiscal year) 67.48% 91.16% 29.88%
Revenue growth, 5-year CAGR — — 9.75%
Net income growth, 5-year CAGR — 0.00% 0.00%

Health

Metric ACTU ICU Biotechnology median
Debt to equity 0.00 0.00 0.00
Current ratio 1.25 1.89 4.89
Net debt to EBITDA 0.59 0.99 1.01

Dividend

Metric ACTU ICU Biotechnology median
Dividend yield — — 0.41%
Payout ratio — — —

Size

Metric ACTU ICU Biotechnology median
Market cap 17.98m 10.20m 172.11m

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