AC Immune (ACIU) vs Sionna Therapeutics, Inc. (SION)

AC Immune and Sionna Therapeutics, Inc. are both Biotechnology companies. AC Immune and Sionna Therapeutics, Inc. are of similar size ($249.4M and $241.9M). Sionna Therapeutics, Inc. has the higher net margin (0.00% vs −1,783.7%) and the lower return on invested capital (−125.0% vs 0.00%). Across the 11 metrics below, Sionna Therapeutics, Inc. leads on 6 and AC Immune on 5.

Valuation

Metric ACIU SION Biotechnology median
P/E n/m n/m 7.88
P/S 53.60 n/m 11.47
P/B 5.59 0.89 2.52
Price to free cash flow n/m n/m 21.16
EV/EBITDA n/m n/m 0.74
EV/Sales 34.13 n/m 10.73
Earnings yield (32.54%) (41.68%) (28.84%)
Free cash flow yield (33.65%) (32.31%) (23.03%)

Profitability

Metric ACIU SION Biotechnology median
Gross margin 100.00% — 65.16%
Operating margin (1,745.75%) 0.00% 0.00%
Net margin (1,783.66%) 0.00% 0.00%
Free cash flow margin 0.00% 0.00% 0.00%
Return on equity 0.00% (32.34%) (57.72%)
Return on assets 0.00% (30.66%) (49.22%)
Return on invested capital 0.00% (125.00%) 0.00%

Growth

Metric ACIU SION Biotechnology median
Revenue growth (TTM) (85.56%) — 5.64%
EPS growth (last fiscal year) (44.83%) 88.24% —
Revenue growth, 5-year CAGR (47.84%) — 8.40%
Net income growth, 5-year CAGR 0.00% — 0.00%

Health

Metric ACIU SION Biotechnology median
Debt to equity 0.00 0.00 0.00
Current ratio 0.93 20.05 4.73
Net debt to EBITDA 1.37 2.58 0.96

Dividend

Metric ACIU SION Biotechnology median
Dividend yield — — 2.10%
Payout ratio 0.00 — 0.00

Size

Metric ACIU SION Biotechnology median
Market cap 249.35m 241.89m 162.10m

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