Tempus AI, Inc.

TEM Healthcare Health Information Services

Tempus AI, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $1.3 billion, up 83.4% from fiscal 2024.

Revenue
+23.1%
EPS
+82.2%
Free cash flow
+95.7%
Total debt
+8.44%

Quarter to September 2026, against a year earlier

76.28 5.85 +8.31%
Market cap
$12.9B
P/E
0.0×
Fwd P/E
−51.8×
Dividend yield
—
F-score
4/9
Altman Z
2.60
Beneish M
−1.25
Dividend safety
n/a

Tempus AI, Inc. 10-K filed Feb 24, 2026

Fiscal year 2025 · Period ended Dec 31, 2025 · Filed · accepted 4:06 PM ET · Document on sec.gov · Filing index

What changed

Item 1, Business, against the 10-K filed Feb 24, 2025: 23 added · 12 removed · 110 modified; 8 with only figures updated; 2 moved without change

  1. Modified · Overview

    We endeavor to unlock the true power of precision medicine by creating Intelligent Diagnostics through the practical application of artificial intelligence, or AI, in healthcare. Intelligent Diagnostics use AI, including generative and agentic AI, to make laboratory tests more accurate, tailored, and personal. We make tests intelligent by connecting laboratory results to a patient’s own clinical data, thereby personalizing the results. Our novel insight was realizing that all laboratory test results, genomic or otherwise, could be contextualized for a specific patient based upon that patient’s unique characteristics, and technology could therefore guide therapy selection and treatment decisions to allow each patient to progress on their own unique path. The drugs recommended, the clinical trials explored, the care pathways evaluated, and the adverse events considered—all have the potential to be refined and enhanced when test results are connected to a patient’s personal profile, enabling the right patient to be routed to the right therapy at the right time.