Protagonist Therapeutics, Inc.

PTGX Healthcare Biotechnology

Protagonist Therapeutics, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $46.0 million, down 89.4% from fiscal 2024. In the quarter to June 2026, revenue grew 3,749.2%, EPS grew 549.1% and free cash flow grew 839.7%, each against the same quarter a year earlier.

128.75 7.80 −5.71%
Market cap
$8.8B
P/E
106×
Fwd P/E
25.0×
Dividend yield
—
F-score
4/9
Altman Z
61.55
Beneish M
−7.18
Dividend safety
n/a

An Income Statement, also known as a Profit and Loss Statement, summarizes a company's revenues, expenses, and profits over a specific period. It highlights how revenue is transformed into net income, showcasing operational efficiency. Key components include total revenue, cost of goods sold (COGS), gross profit, operating expenses, and net profit. Businesses use the Income Statement to assess financial performance, make strategic decisions, and ensure profitability. Investors and stakeholders analyze it to gauge the company’s financial health and future growth potential.

Older periods Sep '25 Dec '25 Mar '26 Jun '26
Revenue

+8 more TTM periods

209.22 46.02 74.06 281.99
Gross Profit
209.22 46.02 74.06 281.99
R&D Expenses
147.84 159.29 170.14 175.16
SG&A Expenses
42.37 44.85 46.39 48.49
Operating Income
19.01 (158.13) (142.46) 58.34
Non-operating Income/Expense
29.06 28.82 27.09 26.00
EBT
48.07 (129.31) (115.37) 84.34
Income Tax Provision
— 2.41 1.33 1.60
Income after Tax
45.91 (130.15) (114.71) 82.91
Net Income Common
45.91 (130.15) (114.71) 82.91
EPS (Basic)
0.75 (2.05) (1.80) 1.22
EPS (Diluted)
0.62 (2.05) (1.81) 1.03
Shares (Basic, Weighted)
62.95 63.45 63.99 64.59
Shares (Diluted, Weighted)
63.83 63.45 65.34 67.21
Gross Margin
100.00% 100.00% 100.00% 100.00%
EBIT Margin
9.09% (343.63%) (192.36%) 20.69%
EBT margin
22.98% (281.01%) (155.78%) 29.91%
Net Profit Margin
21.94% (282.83%) (154.88%) 29.40%
Free Cash Flow Margin
30.45% 121.87% (159.18%) 46.31%
EBITDA
13.04 (162.48) (145.52) 56.38
EBIT
19.01 (158.13) (142.46) 58.34
EPS (Diluted, from Cont. Ops)
0.66 (2.05) (1.81) 1.03
EPS (Diluted, Consolidated)
0.66 (2.05) (1.81) 1.03
EPS (Basic, Consolidated)
0.75 (2.05) (1.80) 1.21
Shares (Diluted, Average)
64.16 63.57 65.45 67.33
EPS (Basic, from Continuous Ops)
0.75 (2.05) (1.80) 1.21
Income from Continuous Operations
45.91 (130.15) (114.71) 82.91
Consolidated Net Income/Loss
45.91 (130.15) (114.71) 82.91
EBITDA Margin
6.23% (353.10%) (196.48%) 19.99%
Operating Cash Flow Margin
31.29% 125.33% (157.48%) 46.53%

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In millions of $ except per-share values · columns are period end dates