Kiniksa Pharmaceuticals International, plc

KNSA Healthcare Drug Manufacturers Specialty & Generic

Kiniksa Pharmaceuticals International, plc’s revenue for fiscal 2025 (year ended December 2025) was $677.6 million, up 60.1% from fiscal 2024.

Revenue
+58.1%
EPS
+142.2%
Free cash flow
+43.5%

Quarter to September 2026, against a year earlier

88.50 7.62 −7.93%
Market cap
$6.9B
P/E
62.1×
Fwd P/E
67.8×
Dividend yield
—
F-score
8/9
Altman Z
10.35
Beneish M
−3.16
Dividend safety
n/a

Kiniksa Pharmaceuticals International, plc (KNSA) Operating margin

Alert me on Operating margin

Kiniksa Pharmaceuticals International, plc's operating margin over the twelve months to 30 September 2026 was 13.8%, up 2.4 percentage points from fiscal 2025 (11.4%). Over the past ten years it has ranged from −406.4% (fiscal 2021) to 11.4% (fiscal 2025) — the current reading is the highest in ten years. That is above the Drug Manufacturers Specialty & Generic industry median of 0.00% and above the Healthcare sector median of 0.00%.

Operating margin, annual

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Annual newest first

Period Operating margin Change (points)
FY2025 11.4% 22.18
FY2024 −10.8% (1.46)
FY2023 −9.32% (13.76)
FY2022 4.44% 410.82
FY2021 −406.4% (406.38)
FY2020 0.00% 0.00
FY2019 0.00% 0.00
FY2018 0.00% 0.00
FY2017 0.00% 0.00
FY2016 0.00% —

Quarterly newest first

Period Operating margin Change (points)
Sep 2026 19.0% 7.81
Jun 2026 11.2% (2.50)
Mar 2026 13.7% 3.88
Dec 2025 9.78% (3.50)
33 more quarters

Against its own ten years

Low −406.4% High 11.4%
Ten-year median 0.00%
Current reading's percentile 100

Operating margin against peers

Company Operating margin
SUPN Indivior Pharmaceuticals Inc. compare 40.6%
LQDA Liquidia Corporation compare 37.4%
LNTH Lantheus Holdings, Inc. compare 18.6%
AMRX AMNEAL PHARMACEUTICALS, INC. compare 15.0%
KNSA Kiniksa Pharmaceuticals International, plc 13.8%
RDY Dr. Reddy's Laboratories Ltd compare 9.20%
ALKS Alkermes plc compare 3.66%
ELAN Elanco Animal Health Incorporated compare 1.61%
HIMS Hims & Hers Health, Inc. compare −5.99%
Drug Manufacturers Specialty & Generic industry median 0.00%
Healthcare sector median 0.00%
Market median 0.00%

What Operating margin is

EBIT Margin tells an investor how much operating profit, before interest and taxes, a company keeps from each unit of revenue.

EBIT ÷ Revenue

The full definition of Operating margin →

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