Axsome Therapeutics, Inc.

AXSM Healthcare Biotechnology

Axsome Therapeutics, Inc.’s revenue for fiscal 2025 (year ended December 2025) was $638.5 million, up 65.5% from fiscal 2024. In the quarter to June 2026, revenue grew 45.5%, EPS fell 2.06%, free cash flow fell 2.98% and total debt rose 4.66%, each against the same quarter a year earlier. Revenue growth for three consecutive years.

157.14 4.65 −2.87%
Market cap
$8.5B
P/E
0.0×
Fwd P/E
−121×
Dividend yield
—
F-score
5/9
Altman Z
6.91
Beneish M
−2.53
Dividend safety
n/a
Dec '25 Dec '24 Dec '23 Dec '22 Dec '21 Dec '20 Dec '19 Dec '18 Dec '17 Dec '16
P/E ratio
0.00 0.00 0.00 0.00 — — — — — —
Piotroski F-Score
5 5 — — — — — — — —
P/S ratio
14.23 10.51 12.94 0.00 — — — — — —
Altman Z-Score
6.91 1.58 3.38 4.86 — — — — — —
P/FCF ratio
0.00 0.00 0.00 0.00 — — — — — —
Altman Z″-Score (non-manufacturers)
(5.64) (6.70) (2.70) (6.04) — — — — — —
P/Operating CF
(487.10) (154.72) (115.29) (108.15) — — — — — —
Beneish M-Score
(2.53) (3.45) 0.15 — — — — — — —
P/B ratio
102.90 71.10 18.33 27.21 — — — — — —
Price to Tangible BV
254.26 0.00 27.86 75.30 — — — — — —
EV/Sales
13.92 10.17 12.17 0.00 — — — — — —
EV/EBITDA
0.00 0.00 0.00 0.00 — — — — — —
EV/Operating CF
(95.13) (30.55) (22.70) (24.68) — — — — — —
EV/FCF
(94.64) (30.49) (22.61) (24.53) — — — — — —
Quick Ratio
1.44 1.99 3.46 2.47 3.75 7.85 8.98 1.29 2.79 5.11
Current Ratio
1.55 2.11 3.63 2.54 3.75 7.85 9.00 1.41 2.90 5.30
Net Debt/EBITDA
1.29 0.49 0.94 0.61 0.30 1.38 3.04 0.32 1.03 0.99
Debt/Assets
17.68% 32.30% 30.27% 28.44% 55.92% 25.96% 7.86% 23.53% 18.74% 24.78%
Debt/Equity
1.38 3.22 0.93 0.86 3.14 0.42 0.10 3.86 0.40 0.44
Asset Turnover
1.01 0.67 0.59 0.24 0.00 0.00 0.00 0.00 0.00 0.00
Operating CF/Net income
0.51 0.45 0.61 0.62 0.83 0.76 0.68 0.97 0.91 0.78
Capex/Depreciation
(0.05) (0.03) (0.06) (0.12) (0.27) (0.05) (0.02) (0.08) (0.02) (1.17)
Interest Coverage
(25.43) (42.71) (35.93) (24.51) (21.89) (38.64) (54.25) (29.14) (20.27) (208.03)
ROE
(252.11%) (231.63%) (159.21%) (298.97%) (201.51%) (70.36%) (76.08%) (350.78%) (151.19%) (79.99%)
ROA
(29.11%) (49.66%) (52.02%) (89.27%) (95.21%) (50.60%) (57.94%) (121.59%) (78.47%) (62.33%)
ROIC
0.00% 0.00% 0.00% (3,779.83%) 0.00% 0.00% 0.00% 0.00% 0.00% 0.00%
Return on Tangible Assets
(86.93%) (112.39%) (65.32%) (124.92%) (204.60%) (64.06%) (34.89%) (696.64%) (124.80%) (87.95%)
Average Days of Receivables
128.32 134.38 127.90 275.00 — — — — — —
Research and Development Expense of Revenue
28.70% 48.50% 36.20% 115.81% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00%
Selling, General and Administrative Expense of Revenue
89.37% 106.65% 119.41% 318.27% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00%
Intangible Assets out of Total Assets
0.08 0.10 0.11 0.21 0.00 0.00 0.00 0.00 0.00 0.00
Share Based Compensation of Revenue
14.68% 22.09% 23.14% 75.40% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00%
Graham Net Nets
0.00 (0.01) 0.03 0.01 — — — — — —
Graham Number
0.00 0.00 0.00 0.00 — — — — — —
Earnings Yield
(2.02%) (7.08%) (6.75%) (6.23%) — — — — — —
Free Cash Flow Yield
(1.03%) (3.17%) (4.16%) (3.93%) — — — — — —
Revenue per Share
12.83 8.05 5.96 1.23 0.00 0.00 0.00 0.00 0.00 0.00
Operating CF per Share
(1.88) (2.68) (3.19) (2.87) (2.88) (2.11) (1.36) (1.12) (1.16) (1.11)
Capex per Share
(0.01) (0.01) (0.01) (0.02) (0.01) 0.00 0.00 0.00 0.00 (0.01)
Free Cash Flow per Share
(1.89) (2.69) (3.21) (2.88) (2.89) (2.11) (1.36) (1.12) (1.16) (1.12)
Cash per Share
6.49 6.58 8.50 4.94 2.30 4.94 6.47 0.52 1.49 1.91
Shareholders Equity per Share
1.77 1.19 4.20 2.69 0.42 3.06 5.25 0.03 0.73 1.13
Interest Debt per Share
0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
Book value per Share
1.77 1.19 4.20 2.69 0.42 3.06 5.25 0.03 0.73 1.13
Free Cash Flow
(93.88) (128.68) (145.66) (117.21) (108.53) (78.50) (46.39) (30.09) (26.48) (21.39)
Working Capital
210.15 254.96 365.41 149.08 63.45 160.59 195.88 4.39 23.12 30.83
Capital Expenditures
(0.48) (0.27) (0.58) (0.70) (0.31) (0.05) (0.02) (0.03) (0.01) (0.10)
Net Current Asset Value
(12.52) (26.42) 107.00 23.72 14.36 111.68 178.55 0.77 16.46 21.36
EV/EBIT
0.00 0.00 0.00 0.00 — — — — — —
Capex to Sales
0.00 0.00 0.00 0.01 0.00 0.00 0.00 0.00 0.00 0.00
Price to Operating Income
0.00 0.00 0.00 0.00 — — — — — —
Other line items
Depreciation/Fixed assets
18.45 18.15 11.12 8.15 4.06 16.44 22.46 8.20 7.53 0.89
Cash ROIC
(17.61%) (23.14%) (19.29%) (28.97%) (71.79%) (22.69%) (11.15%) (162.40%) (46.13%) (31.61%)
Accounts Receivable Turnover
3.48 3.26 4.08 0.00 — — — — — —
Accounts Payable Turnover
0.69 0.59 0.66 0.20 0.09 0.01 0.01 0.01 0.01 0.01
Inventory Turnover
2.17 2.16 2.68 0.00 0.00 0.00 0.00 0.00 0.00 0.00
Average Days of Payables
503.83 789.09 569.65 2,710.82 4,152.89 63,435.78 107,085.91 27,522.05 29,435.62 72,665.27
Days of Inventory on Hand
214.78 172.42 211.94 303.35 0.00 0.00 0.00 0.00 0.00 0.00
Average Receivables
183.23 118.41 66.26 — — — — — — —
Average Payables
68.77 56.34 39.64 25.88 13.33 12.22 7.32 3.56 3.76 2.99
Average Inventory
21.84 15.43 9.73 — — — — — — —
Average Assets
629.15 578.37 459.86 209.63 136.96 203.34 117.96 25.47 36.88 43.64
Average Common Equity
72.65 124.00 150.27 62.59 64.71 146.26 89.83 8.83 19.14 34.01

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