Lyell Immunopharma, Inc. (LYEL) vs Pyxis Oncology, Inc. (PYXS)

Lyell Immunopharma, Inc. and Pyxis Oncology, Inc. are both Biotechnology companies. Lyell Immunopharma, Inc. and Pyxis Oncology, Inc. are of similar size ($250.2M and $248.0M). Pyxis Oncology, Inc. has the higher net margin (0.00% vs −920,285.2%) and the higher return on invested capital (0.00% vs −539.5%). Across the 13 metrics below, Pyxis Oncology, Inc. leads on 7 and Lyell Immunopharma, Inc. on 6.

Valuation

Metric LYEL PYXS Biotechnology median
P/E n/m n/m 7.88
P/S 8,523.53 n/m 11.47
P/B 0.98 16.00 2.52
Price to free cash flow n/m n/m 21.16
EV/EBITDA n/m n/m 0.74
EV/Sales 964.20 n/m 10.73
Earnings yield (130.25%) (49.30%) (28.84%)
Free cash flow yield (75.99%) (37.11%) (23.03%)

Profitability

Metric LYEL PYXS Biotechnology median
Gross margin 100.00% 0.00% 65.16%
Operating margin (949,981.48%) 0.00% 0.00%
Net margin (920,285.19%) 0.00% 0.00%
Free cash flow margin (647,681.48%) 0.00% 0.00%
Return on equity (93.28%) (179.10%) (57.72%)
Return on assets (71.34%) (99.62%) (49.22%)
Return on invested capital (539.53%) 0.00% 0.00%

Growth

Metric LYEL PYXS Biotechnology median
Revenue growth (TTM) (55.00%) — 5.64%
EPS growth (last fiscal year) 38.70% 3.03% —
Revenue growth, 5-year CAGR (65.85%) — 8.40%
Net income growth, 5-year CAGR 0.00% 0.00% 0.00%

Health

Metric LYEL PYXS Biotechnology median
Debt to equity 0.00 0.00 0.00
Current ratio 5.36 1.34 4.73
Net debt to EBITDA 0.94 0.82 0.96

Dividend

Metric LYEL PYXS Biotechnology median
Dividend yield — — 2.10%
Payout ratio 0.00 0.00 0.00

Size

Metric LYEL PYXS Biotechnology median
Market cap 247.99m 250.22m 162.10m

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