Karyopharm Therapeutics Inc. (KPTI) vs Metagenomi Therapeutics, Inc. (MGX)

Karyopharm Therapeutics Inc. and Metagenomi Therapeutics, Inc. are both Biotechnology companies. Metagenomi Therapeutics, Inc. is the larger, with a market value of $43.4M against $39.2M — 1.1× the size. Karyopharm Therapeutics Inc. grew revenue faster over the last twelve months: 6.81% against −59.8%. Karyopharm Therapeutics Inc. has the higher net margin (−153.3% vs −689.2%) and the higher return on invested capital (0.00% vs 0.00%). Across the 15 metrics below, Karyopharm Therapeutics Inc. leads on 9 and Metagenomi Therapeutics, Inc. on 6.

Valuation

Metric KPTI MGX Biotechnology median
P/E n/m n/m 7.88
P/S 0.32 3.19 11.47
P/B n/m 0.38 2.52
Price to free cash flow n/m n/m 21.16
EV/EBITDA n/m 0.49 0.74
EV/Sales 1.58 (3.47) 10.73
Earnings yield (874.99%) (216.52%) (28.84%)
Free cash flow yield (139.70%) (198.11%) (23.03%)

Profitability

Metric KPTI MGX Biotechnology median
Gross margin 95.89% 100.00% 65.16%
Operating margin (56.17%) (741.58%) 0.00%
Net margin (153.28%) (689.20%) 0.00%
Free cash flow margin (44.57%) (632.67%) 0.00%
Return on equity 78.98% (60.61%) (57.72%)
Return on assets (207.90%) (41.91%) (49.22%)
Return on invested capital 0.00% 0.00% 0.00%

Growth

Metric KPTI MGX Biotechnology median
Revenue growth (TTM) 6.81% (59.84%) 5.64%
EPS growth (last fiscal year) (98.37%) 0.00% —
Revenue growth, 5-year CAGR 6.21% — 8.40%
Net income growth, 5-year CAGR 0.00% — 0.00%

Health

Metric KPTI MGX Biotechnology median
Debt to equity (0.76) 0.00 0.00
Current ratio 0.79 4.50 4.73
Net debt to EBITDA (2.03) 1.71 0.96

Dividend

Metric KPTI MGX Biotechnology median
Dividend yield — — 2.10%
Payout ratio 0.00 — 0.00

Size

Metric KPTI MGX Biotechnology median
Market cap 39.24m 43.44m 162.10m

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