Caribou Biosciences, Inc. (CRBU) vs Spruce Biosciences, Inc. (SPRB)

Caribou Biosciences, Inc. and Spruce Biosciences, Inc. are both Biotechnology companies. Caribou Biosciences, Inc. and Spruce Biosciences, Inc. are of similar size ($140.9M and $134.0M). Caribou Biosciences, Inc. grew revenue faster over the last twelve months: 10.0% against −51.3%. Spruce Biosciences, Inc. has the higher net margin (0.00% vs −1,030.4%) and the higher return on invested capital (0.00% vs 0.00%). Across the 15 metrics below, Caribou Biosciences, Inc. leads on 8 and Spruce Biosciences, Inc. on 7.

Valuation

Metric CRBU SPRB Biotechnology median
P/E n/m n/m 7.88
P/S 12.58 24.12 11.47
P/B 1.29 1.41 2.52
Price to free cash flow n/m n/m 21.16
EV/EBITDA n/m n/m 0.74
EV/Sales 1.39 5.95 10.73
Earnings yield (86.40%) (81.65%) (28.84%)
Free cash flow yield (105.20%) (36.12%) (23.03%)

Profitability

Metric CRBU SPRB Biotechnology median
Gross margin 100.00% 100.00% 65.16%
Operating margin (1,090.90%) 0.00% 0.00%
Net margin (1,030.42%) 0.00% 0.00%
Free cash flow margin (1,323.30%) 0.00% 0.00%
Return on equity (78.27%) (105.98%) (57.72%)
Return on assets (56.87%) (82.38%) (49.22%)
Return on invested capital 0.00% 0.00% 0.00%

Growth

Metric CRBU SPRB Biotechnology median
Revenue growth (TTM) 10.02% (51.32%) 5.64%
EPS growth (last fiscal year) 3.64% 47.59% —
Revenue growth, 5-year CAGR (2.03%) — 8.40%
Net income growth, 5-year CAGR 0.00% 0.00% 0.00%

Health

Metric CRBU SPRB Biotechnology median
Debt to equity 0.00 0.08 0.00
Current ratio 6.49 9.23 4.73
Net debt to EBITDA 0.96 1.34 0.96

Dividend

Metric CRBU SPRB Biotechnology median
Dividend yield — — 2.10%
Payout ratio 0.00 0.00 0.00

Size

Metric CRBU SPRB Biotechnology median
Market cap 134.01m 140.88m 162.10m

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