Kyverna Therapeutics, Inc. (KYTX) vs Prothena Corporation plc (PRTA)

Kyverna Therapeutics, Inc. and Prothena Corporation plc are both Biotechnology companies. Kyverna Therapeutics, Inc. and Prothena Corporation plc are of similar size ($432.3M and $427.1M). Kyverna Therapeutics, Inc. has the higher net margin (0.00% vs −80.7%) and the higher return on invested capital (0.00% vs 0.00%). Across the 12 metrics below, Prothena Corporation plc leads on 8 and Kyverna Therapeutics, Inc. on 4.

Valuation

Metric KYTX PRTA Biotechnology median
P/E n/m n/m 7.88
P/S n/m 7.93 11.47
P/B 2.51 1.51 2.52
Price to free cash flow n/m n/m 21.16
EV/EBITDA n/m n/m 0.74
EV/Sales n/m 2.64 10.73
Earnings yield (43.17%) (10.01%) (28.84%)
Free cash flow yield (38.34%) (14.06%) (23.03%)

Profitability

Metric KYTX PRTA Biotechnology median
Gross margin — 100.00% 65.16%
Operating margin 0.00% (101.80%) 0.00%
Net margin 0.00% (80.67%) 0.00%
Free cash flow margin 0.00% (111.49%) 0.00%
Return on equity (87.24%) (14.39%) (57.72%)
Return on assets (68.40%) (12.54%) (49.22%)
Return on invested capital 0.00% 0.00% 0.00%

Growth

Metric KYTX PRTA Biotechnology median
Revenue growth (TTM) — 427.32% 5.64%
EPS growth (last fiscal year) (9.31%) (99.56%) —
Revenue growth, 5-year CAGR — 62.56% 8.40%
Net income growth, 5-year CAGR — 0.00% 0.00%

Health

Metric KYTX PRTA Biotechnology median
Debt to equity 0.15 0.00 0.00
Current ratio 9.06 25.05 4.73
Net debt to EBITDA 1.51 1.46 0.96

Dividend

Metric KYTX PRTA Biotechnology median
Dividend yield — — 2.10%
Payout ratio — 0.00 0.00

Size

Metric KYTX PRTA Biotechnology median
Market cap 432.29m 427.12m 162.10m

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